![]() Hospital files of patients who were diagnosed with benign fibro-osseous lesions (BFOLs) at the oral and maxillofacial unit of MNH between 20 were included in the study. The permission to conduct this study was granted by the Research and Ethical Committee of the Muhimbili University of Health and Allied Sciences (MUHAS). This was a retrospective descriptive cross-sectional hospital-based study that took place at the Oral and Maxillofacial Unit of the Muhimbili National Hospital (MNH) in 2014. This study was designed with the aim of analyzing the clinico-pathological and radiological features of benign fibro-osseous lesions of the jaws in patients treated in the department of oral and maxillofacial surgery at Muhimbili National Hospital, Tanzania. The frequency and specific characteristics of BFOLs in Tanzania have not been extensively studied so far. Typical OD is common in middle-aged black women. To the contrary, OD is reported to be the commonest BFOLs in studies from Brazil and China. Findings from Nigeria indicate that ossifying fibroma is the most prevalent BFOL, while a study from Uganda reported that FD is the most common lesion followed by ossifying fibroma. There are several subtypes of BFOL which includes osseous dysplasia (OD), OF and FD. Therefore, considering the different management for each type of BFOL, a need for accurate diagnosis is of paramount importance for the proper management of these lesions. The central giant cell granuloma (CGCG) have been managed traditionally by local curettage. Whereas, fibrous dysplasia (FD) is managed conservatively because of its self-limiting nature. Ossifying fibroma (OF) require complete enucleated from surrounding bone since it has a high risk of recurrence. ĭespite having similar features, each type of BFOLs have a different treatment modality. This group of lesions is known to encompass common characteristics that include common clinical, radiologic and histopathological features hence they pose considerable diagnostic and therapeutic challenges to clinicians and pathologists. They are characterized by replacement of the normal bone by an often cellular fibrous tissue containing various forms of ossification. ![]() ![]() The benign fibro-osseous lesions (BFOL) are a poorly defined group of lesions that share the same evolutive mechanism. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. They showed several overlapping clinical, radiological and histological features thus a combination of different modalities seems necessary for an accurate diagnosis. Conclusion: In this sample, BFOLs, were slightly more prevalent in females than males, affecting individuals below 40 years at large. The common histological features in all four types of BFOL included presence of: woven bone in fibrous stroma, giant cells, loose collagen and foci of hemorrhage. Majority (>70%) of the BFOLs were radio-opaque. Maxilla was more affected than the mandible. Ossifying fibroma were the most frequent (61.2%), followed by fibrous dysplasia (19.4%). The patient's age at presentation ranged from 5 years to 75 years with a mean age of 29.81 ± 15.28 years. There was a predominance of females (59, 60.2%), with a male to female ratio of 1:1.5. Results: A total of 98 patient's records were retrieved. The collected information included data on demographic characteristics, the duration of the lesion, location of the lesion, presence of swelling, associated symptoms and reported radiological and histological features. Material and methods: A retrospective study of files of patients who were diagnosed with BFOLs from January 2011 to December 2013 was done. Objective: To analyze the clinico-pathological and radiological features of BFOLs of the jaws in patients treated at Muhimbili National Hospital, Tanzania. They encompass common clinical, radiologic and histopathological features and hence pose considerable diagnostic and therapeutic challenges to clinicians and pathologists. * Correspondence: The benign fibro-osseous lesions (BFOL) are characterized by replacement of the normal bone by cellular fibrous tissue containing various forms of ossification. ![]() Vuhahula 3 and Karpal Singh Sohal 2 *ĭepartment of Oral and Maxillofacial Surgery, Mbabane Government Hospital, Mbabane, Swazilandĭepartment of Oral and Maxillofacial Surgery, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzaniaĭepartment of Pathology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
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